Ping-Kun Zhou Selected Research

lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)

1/2020	TIP60 K430 SUMOylation attenuates its interaction with DNA-PKcs in S-phase cells: Facilitating homologous recombination and emerging target for cancer therapy.
1/2020	Vanillin derivative VND3207 activates DNA-PKcs conferring protection against radiation-induced intestinal epithelial cells injury in vitro and in vivo.
1/2020	DNA-PKcs: A Multi-Faceted Player in DNA Damage Response.
1/2020	DNA damage response signaling pathways and targets for radiotherapy sensitization in cancer.
8/2015	The involvement of c-Myc in the DNA double-strand break repair via regulating radiation-induced phosphorylation of ATM and DNA-PKcs activity.
1/2014	Interaction between HIV-1 Tat and DNA-PKcs modulates HIV transcription and class switch recombination.
8/2010	Radiosensitization and growth inhibition of cancer cells mediated by an scFv antibody gene against DNA-PKcs in vitro and in vivo.
5/2010	Inactivation of DNA-dependent protein kinase leads to spindle disruption and mitotic catastrophe with attenuated checkpoint protein 2 Phosphorylation in response to DNA damage.
4/2008	DNA-dependent protein kinase catalytic subunit modulates the stability of c-Myc oncoprotein.
11/2005	Downregulation of c-myc protein by siRNA-mediated silencing of DNA-PKcs in HeLa cells.

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Ping-Kun Zhou Research Topics

Disease

30	Neoplasms (Cancer) 04/2022 - 09/2005
6	Genomic Instability 01/2021 - 11/2005
5	Carcinogenesis 01/2019 - 10/2009
4	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2020 - 05/2010
4	Radiation Injuries (Radiation Sickness) 01/2020 - 04/2007
4	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2019 - 02/2016
2	Fibrosis (Cirrhosis) 04/2020 - 01/2019
2	Nasopharyngeal Neoplasms (Cancer of the Nasopharynx) 01/2019 - 01/2019
2	Colonic Neoplasms (Colon Cancer) 07/2018 - 10/2014
2	Lung Neoplasms (Lung Cancer) 01/2017 - 01/2013
2	Acquired Immunodeficiency Syndrome (AIDS) 01/2014 - 07/2006
2	Polyploidy 09/2012 - 05/2010
1	Thoracic Diseases 01/2021
1	Silicosis 04/2020
1	Wounds and Injuries (Trauma) 12/2019
1	Stroke (Strokes) 01/2019
1	Hodgkin Disease (Hodgkin's Disease) 01/2019
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2019
1	Tongue Neoplasms (Tongue Neoplasm) 01/2019
1	Colorectal Neoplasms (Colorectal Cancer) 07/2018
1	Esophageal Squamous Cell Carcinoma 01/2018
1	Hepatocellular Carcinoma (Hepatoma) 05/2011
1	Virus Diseases (Viral Diseases) 07/2009
1	Chromosome Aberrations (Chromosome Abnormalities) 02/2009
1	Glioma (Gliomas) 04/2008
1	Leukemia 11/2006

Drug/Important Bio-Agent (IBA)

16	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 09/2005
11	lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA 01/2020 - 09/2005
8	Proteins (Proteins, Gene)FDA Link 01/2021 - 11/2005
5	Biological ProductsIBA 01/2019 - 04/2007
4	DNA-Activated Protein KinaseIBA 01/2020 - 09/2005
4	vanillinIBA 12/2019 - 11/2006
4	Messenger RNA (mRNA)IBA 01/2019 - 02/2016
4	bromovaninIBA 01/2018 - 11/2006
3	Long Noncoding RNAIBA 04/2022 - 01/2019
3	Biomarkers (Surrogate Marker)IBA 12/2020 - 04/2007
2	MicroRNAs (MicroRNA)IBA 12/2020 - 01/2018
2	Silicon Dioxide (Silica)FDA LinkGeneric 04/2020 - 01/2019
2	4-hydroxy-3,5-dimethoxybenzaldehydeIBA 01/2020 - 12/2019
2	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2020 - 01/2017
2	Phosphotransferases (Kinase)IBA 08/2015 - 05/2010
2	Small Interfering RNA (siRNA)IBA 09/2012 - 05/2010
1	Environmental DNAIBA 01/2021
1	Histones (Histone)IBA 01/2021
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2020
1	Ligases (Synthetase)IBA 01/2020
1	Discoidin Domain ReceptorsIBA 01/2020
1	hydroxide ionIBA 12/2019
1	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2019
1	Transforming Growth Factor-beta Type II ReceptorIBA 01/2019
1	Antineoplastic Agents (Antineoplastics)IBA 01/2019
1	Erythrocyte Anion Exchange Protein 1 (Band 3 Protein)IBA 01/2019
1	Hemoglobins (Hemoglobin)IBA 01/2019
1	InterleukinsIBA 01/2019
1	Member 2 Group A Nuclear Receptor Subfamily 4IBA 01/2019
1	Beclin-1IBA 09/2018
1	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 09/2017
1	UraniumIBA 09/2017
1	pevonedistatIBA 01/2017
1	olaparibIBA 01/2017
1	Urokinase Plasminogen Activator ReceptorsIBA 10/2014
1	RadonIBA 01/2013
1	Radiation-Sensitizing AgentsIBA 08/2010
1	2-(morpholin-4-yl)benzo(h)chromen-4-oneIBA 05/2010
1	SmokeIBA 10/2009
1	Viral ProteinsIBA 07/2009
1	Oncogene Proteins (Oncogene Protein)IBA 04/2008
1	AntioxidantsIBA 04/2008
1	Pharmaceutical PreparationsIBA 11/2006
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 11/2005

Therapy/Procedure

15	Radiotherapy 04/2022 - 11/2005
8	Therapeutics 09/2021 - 01/2018
6	Drug Therapy (Chemotherapy) 01/2021 - 11/2005
1	Heavy Ion Radiotherapy 01/2019
1	Radiation Dosimeters 02/2009